Published in PLOS One, a systematic literature review from investigators out of University of Sydney found that exercise improved vaccine response to make them more effective.

Their conclusion was based on nine studies of about 550 subjects. People who participated in acute exercise after a vaccination compared to those who rested had significant increase in seroconversion and titer response. Their study also found that increase in age lead to lower responses, though not surprising.

So after you get a vaccine, don’t just sit there and rest. Instead go for a bout of moderate to vigorous exercise session.

E Bohn-Goldbaum et al. Physical activity and acute exercise benefit influenza vaccination response: A systematic review with individual participant data meta-analysis. PLOS ONE . DOI: 10.1371/journal.pone.0268625